Pa'epa'e Teuga ma Pigment Metabolism

Whitening Cosmetics maPigmentMetabolism

Melanin anabolism ua vaevaeina i vaitau eseese. Ua talitonu saienitisi e mafai ona suʻesuʻeina mea paʻepaʻe ma galue mo taimi eseese metabolic.

(1) Laasaga amata o le fa'atupuina o le melanin

① Faʻalavelave i le faʻaliliuga ma / poʻo le glycosylation o tyrosinase; ② Faʻalavelave faʻatonu i le fausiaina o tyrosinase; ③ Pulea o le tyrosinase pe a mae'a fa'aliliu.

(2) Vaitaimi o le fa'atupuina o Melanin
I le avea ai o le enzyme autu ma le faʻatapulaʻaina o le enzyme mo le faʻaogaina o le melanin, o le tyrosinase inhibitors o le suʻesuʻega autu ma le atinaʻeina o le taimi nei. Talu ai o le tele o vailaʻau paʻepaʻe e pei o le phenol ma le catechol derivatives e foliga tutusa ma tyrosine ma le dopa, o vailaʻau paʻepaʻe e suʻeina e masani ona faʻavasegaina e le faʻatauvaʻa poʻo le faʻatauvaʻa o le tyrosinase.

(3) La'asaga tuai o le fa'atupuina o le melanin

①Faʻasaʻo le fesiitaiga o le melanosome; mea o lo'o i ai serine protease inhibitory a'afiaga, e pei o le rwj-50353, 'alo'ese atoatoa i le UBV-induced epidermal pigmentation; soya trypsin inhibitor e iloagofie aafiaga pa'epa'e ae leai sona aafiaga i le oona o sela pigmenti; Niacinamide, e mafai ona taofia le tuʻuina atu o melanocytes i le va o melanocytes ma keratinocytes; ② Melanin dispersion ma metabolism, α-hydroxy acid, free fatty acid ma retinoic acid, faʻaosofia le faʻafouina o le cell ma faʻaleleia keratinocytes melaninized o le aveeseina.

E taua le matauina o le suʻesuʻega ma le faʻaogaina o mea paʻepaʻe e faʻavae i luga o le melanin metabolism o loʻo i luga e le talafeagai mo le puipuia ma le togafitia o le senile plaques. Talu ai o le faiga o le senile plaque formation e fesoʻotaʻi ma le faʻavaeina o le lipofuscin, e masani ona faʻaaogaina mea faʻamalosi antioxidative e faʻatuai ma toe faʻafoʻi ai faʻailoga senile.